Testicular Cancer

What is Testicular Cancer?

Testicular cancer is a malignant tumour that develops in the tissues of the male reproductive organs (the testicles), which are responsible for producing sperm and the male hormone testosterone.

Although it is not one of the most common cancers in the population overall, it is the most common type of cancer in young adults, with a peak incidence between the ages of 20 and 40. The excellent news is that it is one of the cancers with the highest cure rates in modern medicine (often above 95%), especially when diagnosed early.

Risk Factors

  • Cryptorchidism (undescended testicle): This is the main associated risk factor. It occurs when, during childhood, one or both testicles do not descend normally from the abdomen into the scrotum. Even if corrected surgically in childhood, the risk remains slightly higher in adulthood.
  • Family history: Having a brother or father with a history of testicular cancer significantly increases the risk.
  • Personal history: A patient who has already had cancer in one testicle is more likely to develop the disease in the other testicle.
Symptoms and the Importance of Self-Examination

The classic and earliest warning sign of testicular cancer is the presence of a hard lump in the testicle, usually painless.

Other common symptoms include:

  • Sudden increase in size, swelling, or overall hardening of the testicle;
  • A feeling of heaviness, discomfort, or a dull ache in the scrotum or lower abdomen;
  • Severe pain is not the classic initial symptom (it typically occurs with inflammation or testicular torsion), but a testicular mass that causes mild pain requires immediate urological assessment.

Self-examination: As with the recommendation for breast screening in women, every young adult should regularly palpate their testicles (ideally during a hot shower, when the scrotal skin is relaxed) to become familiar with their normal anatomy and detect any changes early.

Fast and Effective Diagnosis

If you notice a suspicious lump, the assessment should not be delayed.

  • Scrotal ultrasound: This is the first-line test—quick and painless. Ultrasound can distinguish almost immediately, with a very high degree of accuracy, whether the detected “mass” is a benign cyst (fluid-filled) or a solid tumour (suspicious for malignancy).
  • Blood tests (tumour markers): Measurement of alpha-fetoprotein (AFP), beta human chorionic gonadotropin (beta-hCG), and lactate dehydrogenase (LDH). Elevated levels of these proteins confirm tumour activity and help define its type and aggressiveness.
  • Computed tomography (CT) scan (TAC): Essential after tumour confirmation for staging (to check for spread to abdominal lymph nodes or the lungs).
Surgical and Complementary Treatments

The approach is multimodal and depends on the stage of the disease.

1. Curative surgery (radical inguinal orchiectomy)

The mandatory first step is surgical removal of the affected testicle. Unlike surgery for benign scrotal conditions, the incision is not made in the scrotal skin, but rather in the inguinal region (the groin), ensuring that the entire tumour and the spermatic cord are removed safely, preventing malignant cells from spreading.

Aesthetic preservation and body image: During the same procedure, the surgeon may implant a testicular prosthesis made of silicone in the scrotum. The aesthetic result is excellent and immediate, minimising the psychological impact of surgery.

2. Fertility preservation (sperm cryopreservation)

Although most men with one remaining healthy testicle can father children naturally, it is essential to recommend and arrange preventive freezing (cryopreservation) of sperm samples before proceeding with adjuvant treatments, safeguarding the young patient’s reproductive future.

3. Adjuvant therapies

After surgery and pathological analysis, no further treatment may be necessary, and the patient may simply move to close surveillance protocols.

In higher-risk cases or when the disease has spread, cycles of chemotherapy (extremely effective and curative in this type of cancer) or sessions of radiotherapy targeted to the abdominal lymph nodes may be prescribed.

Have you noticed a lump in the testicle? Speed is key to successful treatment. Book your Urology appointment now; if you cannot get an appointment within a week, please contact us directly via the form.

Appointment booking

Book your urology appointment with Dr Frederico Furriel, a urologist with consultations in Leiria, Caldas da Rainha and Porto de Mós. Select your preferred location and submit your appointment request.